Treating depression in HIV+ patients improves treatment adherence, viral outcome

first_imgA team of researchers led by a Harvard School of Public Health (HSPH) postdoctoral research fellow and a Massachusetts General Hospital physician report for the first time that using antidepressant medication to treat depression among HIV-positive individuals not only alleviates suffering from depression but improves adherence to HIV antiretroviral medication and virologic outcomes.The study appears in the December 2010 issue of the Archives of General Psychiatry. “The study’s findings provide concrete evidence for why there should be renewed attention to diagnosing and treating depression among people living with HIV/AIDS,” said lead author Alexander Tsai, a psychiatrist and Robert Wood Johnson Health and Society Scholar in the Center for Population and Development Studies at HSPH. “Our study shows that treatment with antidepressant medication can improve HIV antiretroviral therapy adherence and virologic outcomes.”The study, conducted in San Francisco, involved 158 homeless and “marginally housed” HIV-positive men and women, a population generally considered difficult to treat or study. Many had significant psychosocial impairments such as alcohol and illicit drug use, factors that often result in exclusion from most antidepressant medication randomized trials.The analysis was done among participants in the Research on Access to Care in the Homeless (REACH) study, observed between April 2002 and August  2007. The average follow-up time was 2.9 years. During the follow-up period, 38 of the 158 participants died and 17 were “lost” to follow-up (moved away, unable to be contacted, etc.). “During the course of the study, participants who were treated with antidepressant medication increased self-reported antiretroviral adherence by 25% and were twice as likely to achieve complete viral suppression,” Tsai said.“There is an urgent need for HIV care providers to recognize and treat depression among their patients or to refer their patients to mental health specialists for diagnosis and treatment when necessary,” Tsai said.Senior author of the study was David Bangsberg, a Massachusetts General Hospital (MGH) physician specializing in HIV/AIDS research and director of the MGH Center for Global Health. The study was conducted in collaboration with researchers at the University of California, San Francisco, and the University of California, Berkeley.–Marjorie Dwyer Read Full Storylast_img read more

Introducing Tactical Azure Stack for the Intelligent Edge

first_imgHarsh operating environments for both workers and machinery are one of the key challenges in the mining industry. There are still many incidents where casualties happen due to explosions, cave-ins and equipment related accidents. Workers are also facing regular risks due to the toxic operating conditions. To overcome these occupational hazards while maximizing worker safety and efficiency, mining companies are investing in developing smart appliances and systems that harness the power of the Internet-of-Things (IoT).“Connected Mine” is a well-established industrial concept that enables mining companies to infuse IoT within their operations by performing smart data analytics on connected devices at the edge. Worker safety and efficiency procedures such as collision monitoring, remote digging, worker mobility, and augmented reality simulations heavily depend on real-time analysis of a massive amount of telemetry data. This data is generated by thousands of IoT devices and analysed using artificial intelligence to aid in real-time decision making at a mining site. While the public cloud can provide the extensive compute power required for such advanced solutions, connectivity to the surface above and integrating solution components under challenging environmental conditions have always been a barrier for further advancements.This is where hybrid cloud solutions such as Microsoft Azure Stack come into play. As an extension of Microsoft Azure, Azure Stack provides many of the same Azure Services while operating in edge and disconnected sites. It can address latency and connectivity requirements by processing data locally in Azure Stack and then aggregating it in Azure for further analytics, with common application logic across both platforms. The following example is based on the Azure Stack AI at the Edge architecture published by Microsoft. It explains how we can deploy a trained AI model and integrate with local applications running in Azure Stack to provide low-latency intelligence.In this example, an AI model is trained using Azure Machine Learning Service and a Big Data cluster in Microsoft Azure. Next, it is packaged as a containerized application and deployed into an Azure Container Registry. The trained model can then be deployed to a Kubernetes cluster running on Azure Stack. After that, it is integrated with an Azure IoT Hub which receives telemetry data from Azure IoT Edge-enabled devices and the data is scored against the deployed model. The local application places any insights and anomalies from scoring into a queue, for sending to Azure Storage using an Azure Function. The solution in Azure will leverage the data from edge scoring to improve the model while retaining the globally-relevant and compliant insights in the global web application.However, this leads to the question of how to address the challenges described earlier with isolated and harsh operating conditions such as mining sites. An ideal solution would be to leverage the Dell EMC Tactical Azure Stack, a ruggedized and field-deployable product for Azure Stack tactical edge environments. It can provide an Azure consistent cloud to any operating environment with:Limited or no network connectivityFully mobile, or high portability (“2-person lift”) requirementsHarsh conditions, including those requiring military specifications solutionsHigh security requirements, with optional connectivity to Azure Government and Azure Government SecretIn our previous post, we discussed how Dell EMC’s Tactical Azure Stack offering can complement your hybrid cloud strategy with our unique features such as automated patch and update capabilities, PowerEdge hardware management, and integration with Isilon, CloudLink, and Pivotal Cloud Foundry. Today we are pleased to announce that the Dell EMC Tactical Azure Stack will be generally available in the United States, Canada, Australia, and New Zealand from March 22nd onwards. For more information follow Dell EMC Cloud for Microsoft Azure Stack and contact your Dell EMC account representative.last_img read more

Profit ears

first_imgCorn farmers who want to improve their bottom line this year should attend the 2003 Georgia Corn Short Course Jan. 23 at the Rural Development Center in Tifton, Ga.Industry leaders, agronomists, economists, pathologists and water specialists will discuss topics focused on one thing: managing corn for a profit in Georgia in 2003.There will be a sponsored lunch and a business meeting of the Georgia Corn Growers Association. The course is sponsored by the University of Georgia Extension Service, the Agricultural Commodity Commission for Corn and Southeast Farm Press.Registration begins at 8 a.m. For more information, contact your county extension office or call (229) 386-3416. You can register on-line at read more

MARFORSOUTH and partner nations hold Initial Planning Conference for UNITAS 2014

first_img During the last week of September, members of the U. S. Marine Corps Forces South (MARFORSOUTH) and Navy and Marine forces from Brazil, Canada (Army), Chile, Colombia, Mexico, Paraguay, and Peru came together in Miami, FL to initiate planning for UNITAS Partnership of the Americas 2014 (UNITAS-POA 2014). UNITAS POA is the Marine Corps amphibious phase to the Naval exercise UNITAS. UNITAS is an annual U.S. Southern Command (SOUTHCOM)-sponsored exercise representing a half-century legacy of naval cooperation in the Western Hemisphere. This was the first time the Partner Nations (PN) sat down together to begin planning for Partnership of the Americas (POA) 2014. For 2014, POA will focus on improving the participants’ proficiency in the following environments: Countering Transnational Organized Crime; Humanitarian Assistance/Disaster Relief; Military Operations other than War; Crisis Management; and Littoral Warfare, among others. POA began in 2006 as a company level multinational exchange engagement leveraging U.S. Navy ships and assets engaged in the exercise. “The exercise is also the perfect venue to improve tactical interoperability among exercise participants in the areas of Command and Control; Common Operational Picture; Rules of Engagement; Doctrine, Logistics, Tactics, Techniques, and Procedures; and others,” said Augustin Bolanio, Director of Exercises, MARFORSOUTH. Recognizing the potential for a reduction in budgetary resources, the planning team has already considered reducing PN participation from one platoon (36-40 personnel) per participating country to one squad (14 people) per country. U.S. participation has been reduced from a regiment headquarters and battalion size unit with air and logistics support, to a company level unit with logistics-deterrence detachment support and battalion level leadership. Canadian and Mexican forces agreed to participate, and the Mexican Navy will conduct feasibility studies in providing a Mexican amphibious ship for the exercise. the concept of participation, and the availability of having a Mexican amphibious ship for the exercise is being considered. “I think it is a very important activity among the exercises that SOUTHCOM does with its partner nations in the region. In this opportunity, Chile has been asked to host this amphibious exercise with a multinational view where partner nations will share amphibious operations experiences and interoperability capabilities in order to be able to provide support to a country that may be affected by a natural disaster,” said Captain Claudio Escalona, Chilean Partner Nation Liaison Officer at SOUTHCOM. By Dialogo October 04, 2013 Brief history UNITAS is normally conducted in two phases: Atlantic and Pacific. The purpose of UNITAS is to conduct interoperability exercises among multinational forces including matters related to training, combat doctrine, logistics, communication and other matters of inter-service interest. The first seeds for UNITAS were planted in 1958, when the U.S. South Atlantic Force established it to counter Soviet naval activities in the South Atlantic. One year later, U.S. and major South American navies agreed to participate in a series of exercises with a visiting U.S. task-force. UNITAS I was developed in 1960, with the participation of Argentina, Brazil, Chile, Colombia, Ecuador, Peru, Uruguay, Venezuela, and the United States. From 1965-75, there was an increased sophistication of South American forces, paving the way for more advanced exercises. But from the end of the 1970s through 1994, multinational scenarios involving amphibious, surface warfare, and maritime search and rescue operations became the standard. North Atlantic Treaty Organization (NATO) forces also began to participate. center_img In 1999-2000 UNITAS split into two large-scale exercises: UNITAS Atlantic and UNITAS Pacific, and began to address new and emerging threats between 2001-2002, when advanced, complex, and relevant training and scenarios were adopted, including simultaneous and advanced air, surface, and sub-surface threats, advanced air defense, small boat threats, and maritime security. Since 2006, POA has been executed in Argentina, Brazil, Chile, Colombia, Peru, Uruguay, Miami, and Camp Blanding in Jacksonville, Florida. Last year’s POA was cancelled due to budgetary constraints but in 2012 the exercise focused on amphibious operations and regimental amphibious staff planning in connection to Peace Keeping Operations.last_img read more

NAFCU keeps pushing for CU relief as Congress works on packages

first_img ShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr This is placeholder text continue reading » The Senate today is set to vote on another “skinny” version of its proposed Phase 4 relief package that would provide targeted funding for expanded unemployment benefits, schools, vaccine production and distribution, and testing and tracing. Yesterday, the chamber voted on a separate bill addressing funding and improvements for the paycheck protection program (PPP), but the vote failed.Ahead of today’s vote, NAFCU Vice President of Legislative Affairs Brad Thaler wrote Senate Majority Leader Mitch McConnell, R-Ky., and Minority Leader Chuck Schumer, D-N.Y., to urge them to include additional provisions in the skinny package to allow credit unions to better serve their 122 million members and small businesses.Thaler specifically called for including these provisions in any final legislation:providing relief from credit unions’ member business lending (MBL) cap so they can provide more credit to small businesses impacted by the coronavirus pandemic;center_img This post is currently collecting data…last_img read more

Hempstead Shooting Leaves Teen Dead

first_imgSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York A teenager was gunned down in Hempstead over the weekend and investigators are searching for the shooter, Nassau County police said.Officers responded to Washington Street, where they found the 19-year-old victim suffering from gunshot wounds at 8:39 p.m. Saturday, police said.The victim was taken to Winthrop University Hospital, where he was pronounced dead. His identity wasn’t immediately available. Homicide Squad detectives are continuing the investigation.last_img read more

Jose Mourinho: Tottenham coach handed suspended one-match European ban | Football News

first_imgJose Mourinho has been handed a suspended one-match European competition ban, UEFA has announced.The Tottenham head coach was deemed to be responsible for the late kick-off of their Europa League match against Royal Antwerp on October 29.- Advertisement – Spurs were fined 25,000 euros (£23,000) for the late kick-off by UEFA’s control, ethics and disciplinary body (CEDB), as well as a further 3,000 euros for a breach of UEFA’s equipment regulations. The CEDB said the ban was “deferred for a probationary period of one year, starting from the date of the present decision”.Another condition was Tottenham should “ensure their head coach is personally informed of this decision”.- Advertisement – – Advertisement –center_img Mourinho made nine changes for the 1-0 defeat in Belgium, after which the Spurs boss criticised his players and said he faced “easy choices” over future team selections.Scottish champions Celtic have also been fined 7,000 euros for improper conduct related to their Europa League game against Lille on the same night. ANTWERPEN, BELGIUM - OCTOBER 29: Dele Alli of Tottenham Hotspur runs with the ball during the UEFA Europa League Group J stage match between Royal Antwerp and Tottenham Hotspur at Bosuilstadion on October 29, 2020 in Antwerpen, Belgium. Sporting stadiums around Belgium remain under strict restrictions due to the Coronavirus Pandemic as Government social distancing laws prohibit fans inside venues resulting in games being played behind closed doors. (Photo by Dean Mouhtaropoulos/Getty Images)
Image:Mourinho was heavily critical of his side after their 1-0 defeat in Antwerplast_img read more

Rapid testing, disinfection only work if mobility strictly limited: UI Medical School dean

first_imgIt was essential to limit people’s mobility during the rapidly escalating health crisis to flatten the infection curve, Ari added.The country continuously reported dozens of new positive cases every day in the past week. On Friday, it reported 153 new cases, totaling 1,046 accumulative cases with 87 deaths.Earlier, the Medical Professors Council at the medical school released a statement on Thursday for the government to order a lockdown, especially in areas where the spread had been fast like in Jakarta and Surabaya, East Java, because suggestions to engage in physical distancing were not effective enough to make people stay at home.A panel of experts also recommended a lockdown in Jakarta to the President on March 16.Topics : The dean of the University of Indonesia’s Medical School, Ari Fahri Syam, has suggested that all other efforts in containing the spread of the novel coronavirus, such as disinfectant spraying and rapid testing, hinge on the reduced mobility of the population.He reiterated the need for a lockdown to contain the outbreak. “There have been people, including former vice president Jusuf Kalla, who have suggested a lockdown. This is not a new idea. The key is, when a pandemic happens, we try to limit people’s movements,” he said.”If these people consistently stay at home after the disinfection, then the effort will be effective. This will not be the case if they still go in and out of potentially infectious areas,” Ari said on Friday, during an online press conference on the COVID-19 pandemic. Friday’s press conference also addressed public concern about the effectiveness of the rapid mass testing currently taking place in selected areas in the country, particularly in the COVID-19 “red zones” like the capital Jakarta and its neighboring province of West Java.Among those prioritized to get tested are health workers and people with contact history with coronavirus-infected persons, as previously instructed by President Joko “Jokowi” Widodo.Ari explained that some of the rapid test results might come back negative as the virus was still possibly in the “window period”, or the time between infection and when lab tests can identify the infection.”People having contact history with suspected COVID-19 cases or patients who have yet to test negative should still impose the two-week self-quarantine,” he stressed.last_img read more

Wednesday people roundup

first_imgAxiom Alternative Investments – Gildas Surrey is set to join the asset manager as a senior analyst and partner at the beginning of June. Surrey will be based in the London office. He joins from BNP Paribas, where he was a senior analyst in the European banking sector. He also worked at Citigroup and Merrill Lynch.Hermes Investment Management – Ben Patton has been appointed associate director in the investment manager’s real estate debt team. Based in London, Patton will be responsible for the origination and execution of commercial real estate debt transactions. He will report to Vincent Nobel, head of Hermes’ real estate debt platform. Prior to joining Hermes, Patton was vice-president of corporate banking at Barclays Real Estate. Scottish Widows, AMP Capital, Pinsent Masons, Axiom Alternative Investments, HermesScottish Widows – Emma Watkins is set to join the UK insurer as director of bulk annuities as the firm sets up a new business unit. Watkins is currently a partner at consultancy LCP, where she advises pension schemes on bulk annuity deals. She joins Scottish Windows, the insurer owned by the Lloyds Banking Group, on 1 June. She will lead the development of the firm’s new bulk annuities business. Watkins joined LCP from US insurer MetLife, where she led business development for its then bulk annuity business.AMP Capital – Damien Stanley has joined the infrastructure manager as a principal, based in the London office. Stanley will join the infrastructure equity team, reporting to head of origination for Europe Simon Ellis. Stanley was previously chairman of the UK subsidiary of Whitehelm Capital and has also been head of infrastructure investment advice for the EMEA at Morgan Stanley.Pinsent Masons – Ben Fairhead and Julian Sladdin have been promoted to partners in the law firm’s pensions disputes department. The promotions will take effect on 1 May. Fairhead is a litigator in pensions disputes including professional negligence and regulatory disputes. Sladdin specialises in dispute resolution in the Higher Courts with a particular focus on public law challenges.last_img read more

​Chart of the Week: AP7 boosts share of Swedish DC system to record 42%

first_imgAP7, the default fund in the Swedish premium pension system (PPM), now holds a record 42% of all assets in the 7.5m-member first-pillar system, a government report has revealed.In its 2018 report on the six national AP pension funds, the Swedish government published data showing that AP7 managed 42% of the assets in the defined contribution (DC) PPM at the end of 2018. Across all providers on the PPM, assets amounted to SEK1.1trn (€103bn).“The increase is partly due to the inflow of new savers and partly to the fact that the outflow to other funds has decreased,” the report said. “In 2018, funds were also provided through liquidation/closure of funds on the funds marketplace.”The PPM is undergoing a major overhaul, which in late 2018 required all private-sector funds offered on the PPM’s funds marketplace to re-apply for inclusion under new rules. Credit: Kristian Pohl “Fossil fuel investments need to be evaluated based on the fact that fossil fuel use must decrease drastically if we are to reach the climate goals”Per Bolund, Swedish finance ministerIn the report, the government compared the buffer funds’ returns with six similar pension funds in other countries, such as Denmark’s ATP, Norway’s oil fund and Californian public-sector scheme CalPERS.It concluded that for 2018, AP1-4 had higher returns than the average of these funds: down 0.2% compared to a 1.1% average fall.Presenting the report, financial markets minister Per Bolund said that with the funds’ new sustainability requirements, their work towards developing a sustainable financial market would be intensified in the next few years.“Among other things, fossil fuel investments need to be evaluated based on the fact that fossil fuel use must decrease drastically if we are to reach the climate goals,” he said. The government report also said the increase in AP7’s capital was due partly to the fund’s higher return. In 2018, AP7 lost 2.75%, compared with the average result for private funds in the system of a 2.93% decline.Since 2001 when the PPM started, AP7 has produced an average annual return of 6.4%, compared to 3.6% for the private funds, according to the report.AP7’s growth, 2008-18Chart MakerData on the returns produced by the main four buffer funds that back the state pension showed Stockholm-based AP4 had generated the highest returns out of the four funds in the long term.Since the funds were reformed in 2001, AP4’s annual return of 6.1% is the best of the quartet. It also leads its sister funds over 10 years (9.9%) and five years (8.1%).AP1 produced the lowest average annual return since 2001 with 5.6%.None of the funds had achieved their return target in 2018, the government reported, with AP3 leading with a 0.6% gain.AP fund annualised returns after costs (%)Chart MakerInternational comparisonslast_img read more